英文名稱 : Primary Antibody RASA3 Rabbit pAb
貨號(hào):BES25579pab
中文名稱 : 兔 RASA3抗體
交叉反應(yīng) : (Human, Mouse (predicted: Rat, Pig, Cow, Chicken, Dog, Horse )
規(guī)格:100ul、200ul
Host: Rabbit
Isotype: IgG
Clonality: Polyclonal
GeneID: 22821
SWISS: Q14644
Target: RASA3
Applications: WB (1:500-2000) ELISA (1:5000-10000)
Predicted MW.: 91 kDa
Subcellular Location: Cell membrane
Immunogen: KLH conjugated synthetic peptide derived from human RASA3: 501-600/834.
Purification: affinity purified by Protein A
Concentration: 1mg/ml
Storage: 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Background: RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway and is a member of the GAP1 family of GTPase-activating proteins. It stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. RASA3 is an inositol 1,3,4,5-tetrakisphosphate-binding protein (IP4
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